Positron Emission Tomography (PET) scans are some of the most reliable tools for predicting how well a mesothelioma patient will respond to treatment, and also for planning that treatment.
Option conclusion of an team of British researchers who analyzed 15 different studies comparing PET with other styles of tools for diagnosing and staging mesothelioma as well as predicting survival and mortality.
Eleven within the studies evaluated the part of FDG-PET (PET scanning employing a fluorodeoxyglucose marker). A few of those studies found out that malignant mesothelioma cells absorbed a lot of the FDG marker than healthy cells, making FDG-PET an outstanding means for determining the extent of your mesothelioma. Through these studies, patients whose bodies were seen on FDG-PET scan to absorb just about the most on the FDG marker had the shortest survival time. Similarly, mesothelioma patients on chemotherapy who showed a decline in FDG uptake put together to use a extended period until tumor progression.
One study discovered that the FDG-PET technology accurately upstaged 13% and downstaged 27% of mesothelioma cases that has been initially staged using computed tomography (CT).
Four within the 15 studies evaluated the role of FDG-PET along with CT technology (PET-CT) from the diagnosis and prognosis of malignant pleural mesothelioma. One of them studies discovered that primary metastatic mesothelioma lesions (tumors who have spread) has a higher absorption from the FDG than non-metastatic cells. Another study comparing PET-CT to PET alone in staging mesothelioma found PET-CT to always be more accurate.
The scientists who analyzed all of the PET studies concluded -Å"Overall, PET accurately diagnoses malignant pleural mesothelioma and predicts survival and disease recurrence. It will guide further management by predicting the step to chemotherapy and excluding surgery in patients with extrathoracic disease. Combined PET-CT has additional benefits in accurately staging disease.-Â
Case study was published from the journal Interactive Cardiovascular and Thoracic Surgery.
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